A synthetic phospho-peptide corresponding to residues surrounding Tyr705 of human phospho Stat3
Conjugation:
FITC
Alternative Names:
Signal transducer and activator of transcription 3, STAT3, Acute-phase response factor, APRF
Considered an oncogene, Stat3 is constitutively active in 70% of solid and hematological tumors, including leukemia, lymphoma, and multiple myeloma. The IL-6-Jak-Stat3 pathway can mediate cancer inflammation through both mutation of key regulatory genes
Clonality:
Monoclonal
Clone Designation:
[Stat3Y705-B12]
Isotype:
Rabbit IgG1k
Buffer:
1X PBS, 0.09% NaN3, 0.2% BSA
Form:
Conjugated
Application Dilute:
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
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