Btk is a major node in the B-cell receptor signaling pathway, where it regulates B cell maturation, activation, survival, differentiation, and proliferation. Btk is activated by Src family kinases, including Lyn, which phosphorylates Btk at Tyr551. Upon
Clonality:
Monoclonal
Clone Designation:
[BtkY223-B4]
Isotype:
Rabbit IgG1k
Buffer:
1X PBS, 0.09% NaN3, 0.2% BSA
Form:
Conjugated
Application Dilute:
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
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