A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.
Conjugation:
SureLight 488
Alternative Names:
Eukaryotic translation initiation factor 4E-binding protein 1, eIF4E-binding protein 1, PHAS-I, EIF4EBP1
4E-BP1 regulates protein translations induced by upstream signals initiated by ERK1/2 MAP kinase or PI3-Kinase/AKT/mTOR pathways. Ultimately activation of mTOR, positively stimulates mRNA translation by its two dominant downstream substrates: ribosomal p
Clonality:
Monoclonal
Clone Designation:
[4EB1T37T46-A5]
Isotype:
Rabbit IgG1k
Buffer:
1X PBS, 0.09% NaN3, 0.2% BSA
Form:
Conjugated
Application Dilute:
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells or 5 µL per 100 µL of staining volume. It is recommended that the reagent be titrated for optimal performance for each application.
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