TCF/LEF Leeporter(TM) Luciferase Reporter-HEK293 Cell Line

Product Overview

• Article Name: TCF/LEF Leeporter(TM) Luciferase Reporter-HEK293 Cell Line
• Biozol Catalog Number: ABI-14-119ACL
• Supplier Catalog Number: 14-119ACL
• Alternative Catalog Number: ABI-14-119ACL-1VIAL
• Manufacturer: Abeomics
• Category: Zellen/Zellkultur
• Application: FA

Product Description

The TCF/LEF Leeporter(TM) Luciferase Reporter cell line is a stably transfected HEK293 cell line which expresses Renilla luciferase reporter gene under the control of the TCF/LEF response element. This cell line is designed to monitor the transcriptional ac

Application Notes

• Application Dilute: Application: Monitor the TCF/LEF induction activity. Screen for activators or inhibitors of the TCF/LEF signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate

Images

Fig-1: Induction of TCF/LEF activity by LiCl in TCF/LEF Leeporter(TM) - HEK293 cells.

Fig-2: Induction of TCF/LEF activity by Wnt3a in TCF/LEF Leeporter(TM) - HEK293 cells.

Fig-3: Inhibition of Wnt3a-induced TCF/LEF activity by IWR-1 in TCF/LEFLeeporter(TM) - HEK