Polyclonal Antibody to mTOR (Phospho-Ser2448), Rabbit

Product Overview

• Article Name: Polyclonal Antibody to mTOR (Phospho-Ser2448), Rabbit
• Biozol Catalog Number: ABI-35-1207-50
• Supplier Catalog Number: 35-1207-50
• Alternative Catalog Number: ABI-35-1207-50-50UL
• Manufacturer: Abeomics
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human
• Immunogen: Peptide sequence around phosphorylation site of serine 2448 (T-D-S(p)-Y-S) derived from Human mTOR.
• Alternative Names: FRAP|| FRAP1|| FRAP2|| RAFT1

Product Description

Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Amino-acid-signaling to mTORC1 is mediated by Rag GTPases, w

Product Properties

• Clonality: Polyclonal
• Isotype: Rabbit IgG
• NCBI: 2475
• UniProt: P42345
• Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Form: Purified
• Target: mTOR (Phospho-Ser2448)

Application Notes

• Application Dilute: Predicted MW: 289kd, Western blotting: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

Images

Figure 2: Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue u