Human CEACAM-8 / CD66b Protein, His Tag, Unconjugated
Biozol Catalog Number:
ABS-CE8-H5224-1MG
Supplier Catalog Number:
CE8-H5224-1mg
Alternative Catalog Number:
ABS-CE8-H5224-1MG
Manufacturer:
AcroBiosystems
Host:
Human
Category:
Proteine/Peptide
Species Reactivity:
Human
Conjugation:
Unconjugated
Carcinoembryonic antigenrelated cell adhesion molecule 8 (CEACAM8) is also known as CD66b (Cluster of Differentiation 66b), CD66b, CD67, CGM6, NCA95, and is one of seven human CEACAM family members within the immunoglobulin superfamily. CEACAM family members are a set of widely expressed proteins involved in several biological functions, including cell adhesion, migration, signal transduction, and the regulation of gene expression. Abnormal overexpression and downregulation of some CEACAMs have been described in tumor cells. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPIlinked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM8 is a single chain, two Iglike C2type (immunoglobulinlike) domains and one Iglike Vtype (immunoglobulinlike) domain. It is an activation marker for human granulocytes. - Proteine/Peptide