Human IL-17 RA/IL-17 RC (Luc) HEK293 Reporter Cell
Biozol Catalog Number:
ABS-CHEK-ATF133-2VIALS
Supplier Catalog Number:
CHEK-ATF133-2Vials
Alternative Catalog Number:
ABS-CHEK-ATF133-2VIALS
Manufacturer:
AcroBiosystems
Category:
Zellen/Zellkultur
Species Reactivity:
Human
Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6mediated activation of NFkappaB and MAPki
Tag:
Luc
Source:
Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC. Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6-mediated activation of NF-kappa-B and MA
Expression System:
HEK293
Form:
Liquid
Target:
IL-17 RA & IL-17 RC
Application Notes:
Screen for neutralizing antibodies blocking the stimulation of human IL-17A or human IL-17F protein.
CHEK-ATF133-2Vials
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