This protein A purified monoclonal antibody was produced by repeated immunizations with recombinant human p53 protein.
The p53 gene like the Rb gene, is a tumor suppressor gene. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism,
0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2
Purity:
This protein A purified mouse monoclonal antibody reacts specifically with p53 in human tissues and cell lines. The antibody recognizes a 53 kDa band corresponding to p53. Cross reactivity with p53 from other sources has not been determined.
Application Notes:
Anti-p53 has been tested by western blot and immunofluorescence and is suitable for ChIP, flow cytometry, immunohistochemistry, Immunofluorescence, immunoblotting and immunoprecipitation. p53 is the most commonly mutated gene in spontaneously occurring h
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