This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 75-100 of Human Hallen. Hallen is a novel BRCT domain containing protein
Anti-HALLEN plays a role in the DNA damage response pathway by regulating post replication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand