Huwentoxin IV TFA is a selective NaV1.7 channel blocker, which preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 µM).
Molecular Weight:
4220.8
Purity:
>99%
CAS Number:
[526224-73-7 free base]
Formula:
C176H279F3N52O53S6
Target:
Sodium Channel
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