IOX4 is a selective PHD2 inhibitor,IC50 With a value of 1.6 nM, HIFalpha expression is induced in cells and wild-type mice to permeate the blood-brain barrier. IOX4 competes with and displaces 2-oxoglutaric acid (2OG) at the PHD2 active site.
Molecular Weight:
328.33
Purity:
>99%
CAS Number:
[1154097-71-8]
Formula:
C15H16N6O3
Target:
HIF
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