GDC-0077 (RG6114) is a potential best-in-class, orally selective PI3Kalpha inhibitor (IC50=0.038 nM). GDC-0077 (RG6114) exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylation of PIP2 to PIP3. GDC-0077 (RG6114)
Molecular Weight:
407.37
Purity:
>99%
CAS Number:
[2060571-02-8]
Formula:
C18H19F2N5O4
Target:
PI3K
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