Sar-020106 is an ATP-competitive and selective CHK1 inhibitor with an IC50 of 13.3 nM. Sar-020106 has good selectivity to CHK2. Sar-020106 increased cell lethality of Gemcitabine and SN38 by 3.0 to 29 times in a p53-dependent manner in several colon canc
Molecular Weight:
382.85
Purity:
>98%
CAS Number:
[1184843-57-9]
Formula:
C19H19ClN6O
Target:
Checkpoint
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