Jr-ab2-011 is a selective mTORC2 inhibitor with an IC50 value of 0.36 µM. Jr-ab2-011 inhibited mTORC2 activity by blocking the Rictor-MTOR complex (Ki: 0.19 µM). Jr-ab2-011 has anti-glioblastoma multiforme (GBM) activity.
Molecular Weight:
398.28
Purity:
>98%
CAS Number:
[2411853-34-2]
Formula:
C17H14Cl2FN3OS
Target:
mTOR
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