GSK-843 is a potent ATP-competitive RIP3 (RIPK3) kinase inhibitor (IC50 = 6.5 nM) that inhibits TNF/Z-VAD-FMK/IAP agonist-induced cell necrosis in human mice (EC50 range <0.12 to 3 µM).
Molecular Weight:
377.49
Purity:
98.40%
CAS Number:
[1601496-05-2]
Formula:
C19H15N5S2
Target:
RIPK
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