SC144 hydrochloride is the first oral active GP130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, inducing phosphorylation (S782) and deglycosylation of GP130, eliminating Stat3 phosphorylation and nuclear translocation, and further inhibiting th
Molecular Weight:
358.76
Purity:
>98%
CAS Number:
[917497-70-2]
Formula:
C16H11FN6O.HCl
Target:
IL Receptor/Related
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