TH1020 is an effective selective toll-like receptor 5 (TLR5)/ flagellin complex antagonist with IC50 of 0.85 µM. TH1020 inhibits flagellin-induced TLR5 signal transduction, but has no effect on TLR2, TLR3, TLR4, TLR7 and TLR8.
Molecular Weight:
453.54
Purity:
>98%
CAS Number:
[1841460-82-9]
Formula:
C23H15N7S2
Target:
TLR
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