AZD1390 is currently the most effective and highly selective ATM inhibitor with an IC50 of 0.78 nM, oral activity and the ability to cross the blood-brain barrier. In vivo, AZD1390 combined with radiotherapy effectively inhibited tumor growth.
Molecular Weight:
477.57
Purity:
>99.0%
CAS Number:
[2089288-03-7]
Formula:
C27H32FN5O2
Target:
ATM/ATR
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