The original CRC mAb (Y94) used human colorectal carcinoma as immunogen. The original CD3 mAb (JXT3) used human peripheral T lymphocytes as immunogen
This is a bispecific antibody produced by fusion of two hybridoma cell lines. The human colorectal carcinoma antigen (CRC) mAb secreting cell line was transfected by mpSV2gpt. The human CD3 mAb secreting cell line (JXT3) was transfected by mpSV2neo. Th
mAb anti-Human Colorectal Carcinoma/CD3
Clonality:
Monoclonal
Clone Designation:
[BS-1]
Isotype:
IgG1/ IgG2a
Purity:
Protein G affinity purified
Form:
Aff. pur.
Storage:
Store at -20°C
Target:
Human colorectal carcinoma related protein and cluster of differentiation 3 (CD3) on T-cells.
Application Dilute:
Double distilled water is recommended to reconstitute the antibody
Application Notes:
ELISA: The bi-specific antibody has been shown to detect the presence of the tumor-associated antigen in the serum of patients with colorectal carcinoma, and reacted with mucin-like oncofetal pancarcinoma antigen, glycoprotein TAG-72. Fluorescence flow...
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