E.coli-derived human APE1 recombinant protein (Position: P2-L318). Human APE1 shares 94% and 93% amino acid (aa) sequences identity with mouse and rat APE1, respectively.
Alternative Names:
AP endonuclease class I,AP lyase,APE,APE1,APEN,APEX,APEX nuclease,APEX nuclease (multifunctional DNA repair enzyme) 1,apurinic/apyrimidinic (abasic) endonuclease,apurinic-apyrimidinic endonuclease 1,APX,deoxyribonuclease (apurinic or apyrimidinic),DNA-(a
Multifunctional protein that plays a central role in the cellular response to oxidative stress. The two major activities of APEX1 in DNA repair and redox regulation of transcriptional factors. Functions as a apurinic/apyrimidinic (AP) endodeoxyribonuclea