E.coli-derived human ABCB4 recombinant protein (Position: A601-A720). Human ABCB4 shares 79% amino acid (aa) sequence identity with both mouse and rat ABCB4.
Alternative Names:
ABC21,ATP-binding cassette sub-family B member 4,ATP-binding cassette, sub-family B (MDR/TAP), member 4,GBD1,ICP3,MDR2,MDR2/3,MDR3,multidrug resistance protein 3,multiple drug resistance 3,PFIC-3,P-glycoprotein 3,P-glycoprotein-3/multiple drug resistance
Energy-dependent phospholipid efflux translocator that acts as a positive regulator of biliary lipid secretion. Functions as a floppase that translocates specifically phosphatidylcholine (PC) from the inner to the outer leaflet of the canalicular membran