E.coli-derived human SIRT6 recombinant protein (Position: D14-E180). Human SIRT6 shares 95% amino acid (aa) sequence identity with mouse SIRT6.
Alternative Names:
NAD-dependent protein deacetylase sirtuin-6,regulatory protein SIR2 homolog 6,SIR2L6,SIR2-like protein 6,sir2-related protein type 6,sirtuin type 6.
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters an
