Recombinant Human Dickkopf-related protein 1 protein (33-266AA)
Conjugation:
Unconjugated
Alternative Names:
dickkopf 1 homolog,dickkopf-1 like,dickkopf-like protein 1,dickkopf-related protein 1,DKK-1,SK.
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:22000856). DKKs play an important role in vertebrate deve