Recombinant Human E3 ubiquitin-protein ligase RNF114 protein (1-228AA)
Conjugation:
Unconjugated
Alternative Names:
E3 ubiquitin-protein ligase RNF114,PSORS12,RING finger protein 114,RING-type E3 ubiquitin transferase RNF114,zinc finger protein 228,zinc finger protein 313,ZNF313.
E3 ubiquitin-protein ligase promoting the ubiquitination and degradation of the CDK inhibitor CDKN1A and probably also CDKN1B and CDKN1C. These activities stimulate cell cycles G1-to-S phase transition and suppress cellular senescence. May play a role in