Recombinant Human E3 ubiquitin-protein ligase RNF135 protein (339-432AA)
Conjugation:
Unconjugated
Alternative Names:
E3 ubiquitin-protein ligase RNF135,L13,MMFD,REUL,RIG-I E3 ubiquitin ligase,RING finger protein 135,RING finger protein leading to RIG-I activation,RING-type E3 ubiquitin transferase RNF135,Riplet.
Acts as an E2-dependent E3 ubiquitin-protein ligase, involved in innate immune defense against viruses. Ubiquitinates DDX58 and is required for full activation of the DDX58 signaling resulting in interferon beta production.
