Recombinant Human Phorbol-12-myristate-13-acetate-induced protein 1 protein (1-136AA)
Conjugation:
Unconjugated
Alternative Names:
adult T cell leukemia-derived PMA-responsive,APR,immediate-early-response protein APR,NOXA,phorbol-12-myristate-13-acetate-induced protein 1,PMA-induced protein 1,protein Noxa.
Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL