Recombinant Human TNF receptor-associated factor 2 protein (147-281AA)
Conjugation:
Unconjugated
Alternative Names:
E3 ubiquitin-protein ligase TRAF2,MGC:45012,RING-type E3 ubiquitin transferase TRAF2,RNF117,TNF receptor-associated factor 2,TRAP,TRAP3,tumor necrosis factor type 2 receptor associated protein 3,Tumor necrosis factor type 2 receptor-associated protein 3.
Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes Lys-63-linked ubiq
