CFC4,dual specificity mitogen-activated protein kinase kinase 2,ERK activator kinase 2,MAP kinase kinase 2,MAPK/ERK kinase 2,MAPKK2,MEK2,mitogen-activated protein kinase kinase 2, p45,MKK2,PRKMK2.
Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).