MELIOS,SLE1,SLEB1,systemic lupus erythematosus susceptibility 1,TIL3,toll/interleukin-1 receptor-like protein 3,toll-like receptor 5.
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
