DFNA64,diablo homolog, mitochondrial,diablo-like protein,direct IAP-binding protein with low pI,second mitochondria-derived activator of caspase,SMAC.
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform