DR5 antibody was raised against a peptide corresponding to 20 amino acids near the carboxy terminus of human DR5 precursor. The immunogen is located within the last 50 amino acids of DR5.
Conjugation:
Unconjugated
Alternative Names:
apoptosis inducing protein TRICK2A/2B,apoptosis inducing receptor TRAIL-R2,CD262,cytotoxic TRAIL receptor-2,death domain containing receptor for TRAIL/Apo-2L,death receptor 5,DR5,Fas-like protein,KILLER,KILLER/DR5,p53-regulated DNA damage-inducible cell
Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the
