TIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP. The immunogen is located within the last 50 amino acids of TIRP.
Conjugation:
Unconjugated
Alternative Names:
cytoplasmic adaptor,MyD88-4,NF-kappa-B-activating protein 502,putative NF-kappa-B-activating protein 502,TICAM2,TICAM-2,TIR domain-containing adapter molecule 2,TIRAP3,TIRP,TMED7-TICAM2 read-through transcript,toll/interleukin-1 receptor (TIR) domain-con
Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1, signaling is proposed to occur