Anti-EBI-3 antibody (4977) was raised against a peptide corresponding to 16 amino acids near the center of mature human EBI-3. The immunogen is located within amino acids 150 - 200 of EBI3.
Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytoto