Lin28 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Lin28. The immunogen is located within the last 50 amino acids of Lin28.
Conjugation:
Unconjugated
Alternative Names:
CSDD1,LIN28,LIN-28,lin-28A,protein lin-28 homolog A,RNA-binding protein LIN-28,ZCCHC1,zinc finger CCHC domain-containing protein 1,zinc finger, CCHC domain containing 1.
RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism (PubMed:21247876). Seems to recognize a common structural G-quartet (G4) feature in its miR
