Synthesized peptide derived from the C-terminal region of human GRK 2. Location: 570-650aa.
Alternative Names:
BARK1, ADRBK1, BETA-ARK1
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the ac