Synthesized peptide derived from human IGF-IR around the non-phosphorylation site of Y1161. Location: 1100-1180aa.
Alternative Names:
IGFR, CD221, IGFIR, JTK13
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. I
