Cot (phospho Thr290) Antibody, Rabbit, Polyclonal

Product Overview

• Article Name: Cot (phospho Thr290) Antibody, Rabbit, Polyclonal
• Biozol Catalog Number: AST-A0064
• Supplier Catalog Number: A0064
• Alternative Catalog Number: AST-A0064-50, AST-A0064-100
• Manufacturer: Assay Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human COT around the phosphorylation site of Thr290. AA range:256-305
• Alternative Names: MAP3K8, COT, ESTF, Mitogen-activated protein kinase kinase kinase 8, Cancer Osaka thyroid oncogene, Proto-oncogene c-Cot, Serine/threonine-protein kinase cot, Tumor progression locus 2, TPL-2

Product Description

This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases,

Product Properties

• Clonality: Polyclonal
• UniProt: P41279
• Source: Polyclonal, Rabbit IgG
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Application Notes

• Application Dilute: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.