Synthesized peptide derived from human TOP2A (Phospho Ser1213)
Alternative Names:
DNA topoisomerase 2-alpha (EC 5.99.1.3, DNA topoisomerase II, alpha isozyme)
catalytic activity:ATP-dependent breakage, passage and rejoining of double-stranded DNA.,enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.,function:Control of topological states of DNA by transient breakage and subsequent rej