TGFBR1, TGF Beta R1, TGF beta Receptor I, AAT 5, AAT5, Activin A receptor type II like kinase 53kDa, Activin receptor like kinase 5, ACVRLK 4, ACVRLK4, ALK 5, ALK5, Serine/threonine protein kinase receptor R4, SKR 4, SKR4, TbetaR I, TGF beta receptor typ
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptiona