GCK, GK, GLK, Glucokinase, HHF3, HK IV, HK4, HKIV, HXKP, LGLK, MODY2.
Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Glucokinase has a high Km for glucose, and so it is effective only when glucose is abundant. The role of GCK is to provide G6P for the