Noggin belongs to a group of diffusible proteins that bind to ligands of the TGF-beta family, and regulate their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4antagonist whose action was critical for
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1–1.0 mg/ml. Note: Due to solubility reasons the protein should be kept at low pH. Do not vortex. This solution can be stored at 2–8°C for up to 1 week. For extended...
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