Caspase-8 (T341) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: Caspase-8 (T341) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-AP0358
• Supplier Catalog Number: AP0358
• Alternative Catalog Number: BWT-AP0358-50UL,BWT-AP0358-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 310-362 of Human Caspase-8.
• Conjugation: Unconjugated
• Alternative Names: Caspase-8, Caspase8, Caspase 8, CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, MACH, Caspase-8 subunit p18

Product Description

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis, in

Product Properties

• Molecular Weight: ~ 18, 38, 55 kDa
• UniProt: Q14790
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: WB: 1:500~1:1000 IHC: 1:50~1:200
• Application Notes: Caspase 8 (T341) polyclonal antibody detects endogenous levels of full length caspase-8, the cleaved intermediate p43/p41 and the caspase-8 active fragment p18.