Synthetic phosphopeptide derived from human 4E-BP1 around the phosphorylation site of Serine 64.
Conjugation:
Unconjugated
Alternative Names:
Eukaryotic translation initiation factor 4E-binding protein 1, 4E-BP1, eIF4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1, PHAS-I, EIF4EBP1
Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent tran
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Dilute:
WB: 1:500~1:1000 IP: 1:50~1:200
Application Notes:
4E-BP1 (Phospho-Ser64) polyclonal antibody detects endogenous levels of 4E-BP1 protein only when phosphorylated at Ser64.
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