Synthetic phosphopeptide derived from human Akt around the phosphorylation site of Serine 473.
Conjugation:
Unconjugated
Alternative Names:
RAC-alpha serine/threonine-protein kinase, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC
Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Application Dilute:
WB: 1:5000~1:10000 IF: 1:50~1:200 IP: 1:50~1:200
Application Notes:
Akt (Phospho-Ser473) polyclonal antibody detects endogenous levels of Akt protein only when phosphorylated at Ser473.
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