BACE (D492) polyclonal antibody, Unconjugated, Rabbit

Product Overview

• Article Name: BACE (D492) polyclonal antibody, Unconjugated, Rabbit
• Biozol Catalog Number: BWT-BS1382
• Supplier Catalog Number: BS1382
• Alternative Catalog Number: BWT-BS1382-50UL,BWT-BS1382-100UL
• Manufacturer: Bioworld Technology
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthetic peptide, corresponding to amino acids 480-520 of Human BACE.
• Conjugation: Unconjugated
• Alternative Names: Beta-secretase 1, Aspartyl protease 2, ASP2, Asp 2, Beta-site amyloid precursor protein cleaving enzyme 1, Beta-site APP cleaving enzyme 1, Memapsin-2, Membrane-associated aspartic protease 2, BACE1, BACE, KIAA1149

Product Description

Autosomal dominant Alzheimers disease is caused by mutations in the gene encoding the beta-amyloid protein precursor (APP). Amyloid beta-peptide(Abeta), the major feature of amyloid plaques in Alzheimers patients, is the product of APP cleavage by beta- and gamma-secr

Product Properties

• Molecular Weight: ~ 50 kDa
• UniProt: P56817
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
• Form: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Application Notes

• Application Dilute: IHC: 1:50~1:200 IF: 1:50~1:200
• Application Notes: BACE (D492) polyclonal antibody detects endogenous levels of BACE protein.