Association of the receptor Fas with its ligand FasL triggers an apoptotic pathway that plays an important role in immune regulation, development, and progression of cancers. Loss of function mutation in either Fas (lpr mice) or FasL (gld mice) leads to
The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Mouse IgG1. Liquid in PBS, pH 7.3, and 0.02% sodium azide.
Application Dilute:
IF (1/50 - 1/200)
Application Notes:
Recognizes human CD95
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