Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.
The monoclonal antibody was affinity-purified from Syrian hamster antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Syrian Hamster IgG. Liquid in PBS, pH 7.3, and 0.02% sodium azide.
Application Dilute:
IF (1/50 - 1/200)
Application Notes:
Recognizes mouse CD28
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