Programmed cell death 1 ligand 1 (PD-L1, B7-H1, CD274) is a member of the B7 family of cell surface ligands that regulate T cell activation and immune responses. The PD-L1 ligand binds the PD-1 transmembrane receptor and inhibits T cell activation. PD-L1
The monoclonal antibody was affinity-purified from Rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form:
Rat IgG2b kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.
Application Dilute:
IF (1/50 - 1/200)
Application Notes:
Recognizes mouse CD274
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