Caspase 8 monoclonal antibody, Unconjugated, Mouse

Catalog Number: BWT-MB65897
Article Name: Caspase 8 monoclonal antibody, Unconjugated, Mouse
Biozol Catalog Number: BWT-MB65897
Supplier Catalog Number: MB65897
Alternative Catalog Number: BWT-MB65897-50UL,BWT-MB65897-100UL
Manufacturer: Bioworld Technology
Host: Mouse
Category: Antikörper
Application: IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein corresponding to human Caspase 8.
Conjugation: Unconjugated
Alternative Names: MCH5, Caspase-8, CASP-8, Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, FLICE, ICE-like apoptotic protease 5, MORT1-associated ced-3 homolog, MACH
Apoptosis induced through the CD95 receptor (Fas/APO-1) and tumor necrosis factor receptor 1 (TNFR1) activates caspase-8 and leads to the release of the caspase-8 active fragments, p18 and p10 (1-3). Activated caspase-8 cleaves and activates downstream e
Molecular Weight: ~ 57 kDa
UniProt: Q14790
Purity: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Form: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Application Dilute: WB (1/1000 - 1/2000), IHC (1/200 - 1/500)
Application Notes: Recognizes endogenous levels of Caspase 8 protein.