AEE788 is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCalpha and CDK1. Phase 1/2.
Molecular Weight:
440.58
CAS Number:
[497839-62-0]
Formula:
C27H32N6
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